Availability (in Japan)
10 or more
(In Japan at 00:05,
Jan 23, 2025 in JST)
Size
100 µL (1 mg/mL)
Data | |||||
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Clonality | Polyclonal | Clone | Polyclonal | ||
Isotype (Immunized Animal) | Rabbit Ig (aff.) | ||||
Applications |
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Reactivity [Gene ID] | Human[8731] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | RNA (guanine-7-) methyltransferase, MET, Met, CMT1, cm1p, hMet, CMT1c, hCMT1, RG7MT1 | ||||
Background | The 5’-terminal 7-methylguanosine cap (m7GpppN) is the unique structure added to the 5’-end of the nascent RNA through the pre-mRNA processing. The 7-methylguanosine cap protects the mRNA from degradation and acts as binding site for ribosome during translation initiation. RNA (guanine-7-) methyltransferase (RNMT) is the enzyme that catalyzes the methylation of the guanosine cap at the N-7 position to produce the 7-methylguanosine cap. RNMT consists of a methyltransferase domain and an N-terminal non-catalytic domain that required for RNMT recruitment to transcription initiation sites. |
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Related products | RN1001 RIP-Assay Kit RN019M Anti-2,2,7-trimethylguanosine (m3G/TMG) mAb RN016M Anti-7-methylguanosine (m7G)-Cap mAb RN017M Anti-7-methylguanosine (m7G) mAb |
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