Code No. | RN124PW | Print out |
Anti-RNMT (Human) pAb | ||
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, Mar 29, 2024 in JST) |
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Clonality | Polyclonal | |
Clone | Polyclonal | |
Isotype (Immunized Animal) |
Rabbit Ig (aff.) | |
Applications | WB 1:500 IP 5 µL/500 µL of cell extract from 1 x 107 cells/sample |
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Reactivity [Gene ID] | Human[8731] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | RNA (guanine-7-) methyltransferase, MET, Met, CMT1, cm1p, hMet, CMT1c, hCMT1, RG7MT1 | |
Background | The 5’-terminal 7-methylguanosine cap (m7GpppN) is the unique structure added to the 5’-end of the nascent RNA through the pre-mRNA processing. The 7-methylguanosine cap protects the mRNA from degradation and acts as binding site for ribosome during translation initiation. RNA (guanine-7-) methyltransferase (RNMT) is the enzyme that catalyzes the methylation of the guanosine cap at the N-7 position to produce the 7-methylguanosine cap. RNMT consists of a methyltransferase domain and an N-terminal non-catalytic domain that required for RNMT recruitment to transcription initiation sites. |
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Related products | RN1001 RIP-Assay Kit RN019M Anti-2,2,7-trimethylguanosine (m3G/TMG) mAb RN016M Anti-7-methylguanosine (m7G)-Cap mAb RN017M Anti-7-methylguanosine (m7G) mAb |
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Product category | Research area:RNA-RNP Network Epigenetics Brands:RiboCluster Profiler™ |
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Data |