IMMUTEX™ Latex particles
for immunodiagnostic reagents
Latex particles for immunodiagnostic reagents
IMMUTEX™ is a uniform-sized polystyrene latex (PSL) particle for agglutination tests. A variety of particle sizes and surface chemistries of IMMUTEX™ is available to meet your requirements to control sensitivity and dynamic range.
Feature
● Wide choice of particle size from 0.05 µm to 0.48 µm
● Uniform-sized particles
● Variety of surface chemistry
● Ready-to-use, no further purification needed
Specifications
| Diameter | 0.05 µm～0.5 µm |
|---|---|
| Surface Charge Density | ～0.4 mmol/g（～150 Å2/COOH） |
| Solid Content | 5 or 10% |
| pH | 7～9 |
| Solution | 0.09% sodium azide in water |
Type
● IMMUTEX™ Plain Series (hydrophobic adsorption)
IMMUTEX™ Plain Series is a plain polystyrene latex particle which has no or ultra-low carboxyl groups
on its surface.
This series is suitable for physical adsorption of antibodies or antigens.
● IMMUTEX™ Carboxyl Series (covalent attachment)
IMMUTEX™ Carboxyl Series is a carboxylated polystyrene latex particle suitable for covalent coupling
of antibodies or antigens.
Products List
IMMUTEXTM™ Plain Series (hydrophobic adsorption)
IMMUTEX™ Plain Series is a plain polystyrene latex particle which has no or ultra-low carboxyl groups on its surface. This series is suitable for physical adsorption of antibodies or antigens.
| Code No. | Product | Diameter (µm) | Solids Content (wt%) |
|---|---|---|---|
| J-IM-P2015 | IMMUTEX™ P2015, Plain, 0.07-0.11 µm | 0.07 - 0.11 | 5 |
| J-IM-P2116 | IMMUTEX™ P2116, Plain, 0.10-0.14 µm | 0.10 - 0.14 | 10 |
| J-IM-P2117 | IMMUTEX™ P2117, Plain, 0.10-0.16 µm | 0.10 - 0.16 | 5 |
| J-IM-P2118 | IMMUTEX™ P2118, Plain, 0.14-0.21 µm | 0.14 - 0.21 | 10 |
| J-IM-P2245 | IMMUTEX™ P2245, Plain, 0.16-0.22 µm | 0.16 - 0.22 | 10 |
| J-IM-P2246 | IMMUTEX™ P2246, Plain, 0.21-0.27 µm | 0.21 - 0.27 | 10 |
IMMUTEXTM™ Carboxyl Series (covalent attachment)
IMMUTEX™ Carboxyl Series is a carboxylated polystyrene latex particle suitable for covalent coupling of antibodies or antigens.
| Code No. | Product | Diameter (µm) |
COOH*1 (mmol/g) |
Solids Content (wt%) |
|---|---|---|---|---|
| J-IM-P0001 | IMMUTEX™ P0001, Carboxyl, 0.05-0.09 µm | 0.05 - 0.09 | 0.15 - 0.22 | 5 |
| J-IM-P0014 | IMMUTEX™ P0014, Carboxyl, 0.07-0.10 µm | 0.07 - 0.10 | 0.25 - 0.35 | 5 |
| J-IM-P0011 | IMMUTEX™ P0011, Carboxyl, 0.07-0.11 µm | 0.07 - 0.11 | 0.14 - 0.21 | 5 |
| J-IM-P0115 | IMMUTEX™ P0115, Carboxyl, 0.08-0.13 µm | 0.08 - 0.13 | 0.11 - 0.17 | 5 |
| J-IM-P0117 | IMMUTEX™ P0117, Carboxyl, 0.11-0.17 µm | 0.11 - 0.17 | 0.05 - 0.08 | 5 |
| J-IM-P0112 | IMMUTEX™ P0112, Carboxyl, 0.12-0.18 µm | 0.12 - 0.18 | 0.08 - 0.12 | 5 |
| J-IM-P0113 | IMMUTEX™ P0113, Carboxyl, 0.17-0.23 µm | 0.17 - 0.23 | 0.06 - 0.09 | 10 |
| J-IM-P0219 | IMMUTEX™ P0219, Carboxyl, 0.16-0.24 µm | 0.16 - 0.24 | 0.06 - 0.11 | 10 |
| J-IM-P0322 | IMMUTEX™ P0322, Carboxyl, 0.25-0.31 µm | 0.25 - 0.31 | 0.04 - 0.07 | 10 |
| J-IM-P0307 | IMMUTEX™ P0307, Carboxyl, 0.32-0.48 µm | 0.32 - 0.48 | 0.03 - 0.05 | 10 |
*1 Conductometric titration method
Related Products
Blockmaster™ FULLY CHEMICAL SYNTHESIZED BLOCKING REAGENT
The Blockmaster™ series consists of several synthetic water soluble polymer blocking reagents that solve the safety, quality and purity issues often observed when using “standard” protein based blocking solutions.
Blockmaster™ CE series
Blockmaster™ CE510 and CE210 are fully synthetic, water soluble blocking reagents consisting of a hydrophilic PEG tail and multiple amine-end groups. While the PEG tail reduces the non-specific binding, the amine end-group allows for a covalent conjugation with amine reactive surfaces.
| Code No. | Product | Size |
|---|---|---|
| J-CE210RAN | Blockmaster™ CE210 | 100 mL |
| J-CE510RAN | Blockmaster™ CE510 | 100 mL |
Blockmaster™ DB1130
Blockmaster™ DB1130 is a fully synthetic, water soluble polymer blocking reagent consisting of both hydrophilic and hydrophobic units. The optimized combination of hydrophilic and hydrophobic units strongly reduces the non-specific binding and greatly enhances colloidal stability of latex and magnetic beads.
| Code No. | Product | Size |
|---|---|---|
| J-DB1130 | Blockmaster™ DB1130 | 100 mL |
Blockmaster™ PA1080
Blockmaster™ PA1080 is a fully synthetic, water soluble polymer blocking reagent consisting of both hydrophilic and hydrophobic units. The optimized combination of hydrophilic and hydrophobic units realizes excellent protein/cell blocking properties on a wide variety of substrate materials.
| Code No. | Product | Size |
|---|---|---|
| J-PA1080 | Blockmaster™ PA1080 | 100 mL |
References
- Okubo T., Microspcopic observation of ordered colloids in sedimentation equilibrium and the important role of Debye screening lentch. 3. Heavy and monodisperse polystyrene type spheres in aqueous solution of neutral polymers. Colloid Polm Sci., 265, 597-603, 1987
- Kitano T., et al., Kinetic analysis of association process between oppositely charged polymer latex. J. Am. Chem. Soc., 109, 6641-6644, 1987
- Fujikawa H., et al., Rotating the plane of imposed vibration can rotate the plane of flagellar beating in sea-urchin sperm without twisting the axoneme. Appl. Envir. Microbiol., 54(10), 2345-2348, 1988
- Shingyoji C., et al., Latex agglutination test: A simple, rapid and practical method for bovine serum CRP determination. J Cell Sci., 98, 175-181, 1991
- Sarikaputi M., et al., Siginificance of modes of adherence in esophageal Candida albicans. Japanese J, Vererinary Res., 40(1), 1-12, 1992
- Hoshika K., et al., Siginificance of modes of adherence in esophageal Candida albicans. J. Gastroenterology, 29(1), 1-5, 1994
- Fujimura T., et al., Observation of local light propagation in ordered latex layers by scanning near-field optical microscope. Materials Sci Eng, 48(1,2), 94-102, 1997
- Takizawa T., et al., Ultrastructural localization of S100A3, a cycteine-rich, calcium binding protein, in human scalp hair shafts revealed by rapid-freezing immunocytochemistry. J. Histochem Cytochem., 47(4), 525-532, 1999
- Mori Y., et al., Particle deposition in evaporating droplets of polystyrene latex suspension on hydrophilic and hydrophobic substrates. J. Chem. Eng. Jpn., 37(5), 657-661, 2004
IMMUTEX is a trademark of JSR corporation.