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IMMUTEX™ Latex particles
for immunodiagnostic reagents



Latex particles for immunodiagnostic reagents

TEM PhotografhIMMUTEX Latex particles for immunodiagnostic reagents IMMUTEX™ is a uniform-sized polystyrene latex (PSL) particle for agglutination tests. A variety of particle sizes and surface chemistries of IMMUTEX™ is available to meet your requirements to control sensitivity and dynamic range.



Feature

● Wide choice of particle size from 0.05 µm to 0.48 µm
● Uniform-sized particles
● Variety of surface chemistry
● Ready-to-use, no further purification needed


Specifications

Diameter  0.05 µm~0.5 µm
Surface Charge Density  ~0.4 mmol/g(~150 Å2/COOH)
Solid Content  5 or 10%
pH  7~9
Solution  0.09% sodium azide in water

Type

IMMUTEX™ Plain Series (hydrophobic adsorption)
  IMMUTEX™ Plain Series is a plain polystyrene latex particle which has no or ultra-low carboxyl groups
  on its surface.
  This series is suitable for physical adsorption of antibodies or antigens.

IMMUTEX™ Carboxyl Series (covalent attachment)
  IMMUTEX™ Carboxyl Series is a carboxylated polystyrene latex particle suitable for covalent coupling
  of antibodies or antigens.



Products List

IMMUTEXTM™ Plain Series (hydrophobic adsorption)

IMMUTEX™ Plain Series is a plain polystyrene latex particle which has no or ultra-low carboxyl groups on its surface. This series is suitable for physical adsorption of antibodies or antigens.

Code No. Product Diameter (µm) Solids Content (wt%)
J-IM-P2015 IMMUTEX™ P2015, Plain, 0.07-0.11 µm 0.07 - 0.11 5
J-IM-P2116 IMMUTEX™ P2116, Plain, 0.10-0.14 µm 0.10 - 0.14 10
J-IM-P2117 IMMUTEX™ P2117, Plain, 0.10-0.16 µm 0.10 - 0.16 5
J-IM-P2118 IMMUTEX™ P2118, Plain, 0.14-0.21 µm 0.14 - 0.21 10

IMMUTEXTM™ Carboxyl Series (covalent attachment)

IMMUTEX™ Carboxyl Series is a carboxylated polystyrene latex particle suitable for covalent coupling of antibodies or antigens.

Code No. Product Diameter
(µm)
COOH*1
(mmol/g)
Solids
Content
(wt%)
J-IM-P0001 IMMUTEX™ P0001, Carboxyl, 0.05-0.09 µm 0.05 - 0.09 0.15 - 0.22 5
J-IM-P0011 IMMUTEX™ P0011, Carboxyl, 0.07-0.11 µm 0.07 - 0.11 0.14 - 0.21 5
J-IM-P0112 IMMUTEX™ P0112, Carboxyl, 0.12-0.18 µm 0.12 - 0.18 0.08 - 0.12 5
J-IM-P0113 IMMUTEX™ P0113, Carboxyl, 0.17-0.23 µm 0.17 - 0.23 0.06 - 0.09 10
J-IM-P0307 IMMUTEX™ P0307, Carboxyl, 0.32-0.48 µm 0.32 - 0.48 0.03 - 0.05 10

 *1 Conductometric titration method


Related Products

Blockmaster™ FULLY CHEMICAL SYNTHESIZED BLOCKING REAGENT

The Blockmaster™ series consists of several synthetic water soluble polymer blocking reagents that solve the safety, quality and purity issues often observed when using “standard” protein based blocking solutions.


Blockmaster™ CE series

Blockmaster™ CE510 and CE210 are fully synthetic, water soluble blocking reagents consisting of a hydrophilic PEG tail and multiple amine-end groups. While the PEG tail reduces the non-specific binding, the amine end-group allows for a covalent conjugation with amine reactive surfaces.

Code No. Product Size
J-CE210RAN Blockmaster™ CE210 100 mL
J-CE510RAN Blockmaster™ CE510 100 mL

Blockmaster™ DB1130

Blockmaster™ DB1130 is a fully synthetic, water soluble polymer blocking reagent consisting of both hydrophilic and hydrophobic units. The optimized combination of hydrophilic and hydrophobic units strongly reduces the non-specific binding and greatly enhances colloidal stability of latex and magnetic beads.

Code No. Product Size
J-DB1130 Blockmaster™ DB1130 100 mL

Blockmaster™ PA1080

Blockmaster™ PA1080 is a fully synthetic, water soluble polymer blocking reagent consisting of both hydrophilic and hydrophobic units. The optimized combination of hydrophilic and hydrophobic units realizes excellent protein/cell blocking properties on a wide variety of substrate materials.

Code No. Product Size
J-PA1080 Blockmaster™ PA1080 100 mL

References

  • Okubo T., Microspcopic observation of ordered colloids in sedimentation equilibrium and the important role of Debye screening lentch. 3. Heavy and monodisperse polystyrene type spheres in aqueous solution of neutral polymers. Colloid Polm Sci., 265, 597-603, 1987
  • Kitano T., et al., Kinetic analysis of association process between oppositely charged polymer latex. J. Am. Chem. Soc., 109, 6641-6644, 1987
  • Fujikawa H., et al., Rotating the plane of imposed vibration can rotate the plane of flagellar beating in sea-urchin sperm without twisting the axoneme. Appl. Envir. Microbiol., 54(10), 2345-2348, 1988
  • Shingyoji C., et al., Latex agglutination test: A simple, rapid and practical method for bovine serum CRP determination. J Cell Sci., 98, 175-181, 1991
  • Sarikaputi M., et al., Siginificance of modes of adherence in esophageal Candida albicans. Japanese J, Vererinary Res., 40(1), 1-12, 1992
  • Hoshika K., et al., Siginificance of modes of adherence in esophageal Candida albicans. J. Gastroenterology, 29(1), 1-5, 1994
  • Fujimura T., et al., Observation of local light propagation in ordered latex layers by scanning near-field optical microscope. Materials Sci Eng, 48(1,2), 94-102, 1997
  • Takizawa T., et al., Ultrastructural localization of S100A3, a cycteine-rich, calcium binding protein, in human scalp hair shafts revealed by rapid-freezing immunocytochemistry. J. Histochem Cytochem., 47(4), 525-532, 1999
  • Mori Y., et al., Particle deposition in evaporating droplets of polystyrene latex suspension on hydrophilic and hydrophobic substrates. J. Chem. Eng. Jpn., 37(5), 657-661, 2004

IMMUTEX is a trademark of JSR corporation.



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