Magnosphere™ MS160/Tosyl & MS300/Tosyl are magnetic particles especially for high purity bioseparation. The surface of these particles are coated with hydrophilic polymer for reducing non-specific binding and are activated with p-toluene sulfonyl (tosyl) group. The Tosyl group enables to immobilize ligands such as antibody without using coupling reagents. The activated Tosyl group is eliminated though a coupling reaction, the surface of the particles became hydrophilic to reduce non-specific binding.
Uniform particle size and superparamagnetic property of the Magnosphere™
MS160/Tosyl & MS300/Tosyl provide good magnetic separation and re-suspension response.
● Uniform particle diameter
● Superparamagnetic
● High-speed magnetic response
● Low non-specific binding
| MS160/Tosyl | MS300/Tosyl | |
|---|---|---|
| Particle size | 1.5 µm | 3 µm |
| Surface carboxyl density | 150 nmol/mg beads approx. | 80 nmol/mg beads approx. |
| Ligand coupling | Covalent coupling | Covalent coupling |
| Application | Immunoassay | Immunoassay |
| Code No. | Product | Surface | Diameter (µm) |
Function Density (Tosyl) (µmol/g) |
Particle Contents (%) |
Volume (mL) |
Preservative |
|---|---|---|---|---|---|---|---|
| J-MS-S160T | MS160/Tosyl | Hydrophilic | 1.5 | 150 | 1 | 4 | Proclin 950 |
| J-MS-S300T | MS300/Tosyl | Hydrophilic | 3 | 80 | 1 | 4 | Proclin 950 |