Anti-IGFBP6 (Human) mAb

Availability (in Japan)

10 or more

（In Japan at 00:05,
Feb 18, 2019 in JST）

Size

100 µg/100 µL

Data	Flow Cytometry
Clonality	Monoclonal	Clone	2H8-1
Isotype (Immunized Animal)	Mouse IgG2aκ
Applications	FCM 1-10 µg/mL
Immunogen (Antigen)	Human IGFBP6 expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity [Gene ID]	Human[3489]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	－２０°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	IBP-6, IGF binding protein 6, IGF-binding protein 6, IGFBP-6, insulin-like growth factor-binding protein 6
Background	Insulin-like growth factor-binding protein 6 (IGFBP6) is a secreted protein that consists of an IGFBP N-terminal domain and a thyroglobulin type-1 domain. IGFBP6 is secreted as an autocrine growth inhibitor in the human keratinocyte cell line HaCat. Recombinant IGFBP6 can inhibit the growth of HaCat cells and other keratinocyte cell lines. It also inhibits the growth of a number of IGF-II-dependent cancers including rhabdomyosarcoma, neuroblastoma, and colon cancer.
Related products	W029-3 Anti-IGFBP1 (Human) mAb M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) W147-3 Anti-TYRO3 (Human) mAb W164-3 Anti-RHBDD3 (Human) mAb
References	Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat Biotechnol. 17, 487-90 (1999)（PMID: 10331810）
Product category	Research area Cancer Tools Flow cytometry reagents

The availability is based on the information in Japan at 00:05, Feb 18, 2019 in JST.
The special price is shown in red color.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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