Availability (in Japan)
10 or more
(In Japan at 00:05,
Feb 18, 2019 in JST)
Size
100 µg/100 µL
Data | |||||
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Clonality | Monoclonal | Clone | 2H8-1 | ||
Isotype (Immunized Animal) | Mouse IgG2aκ | ||||
Applications |
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Immunogen (Antigen) | Human IGFBP6 expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening). | ||||
Reactivity [Gene ID] | Human[3489] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | IBP-6, IGF binding protein 6, IGF-binding protein 6, IGFBP-6, insulin-like growth factor-binding protein 6 | ||||
Background | Insulin-like growth factor-binding protein 6 (IGFBP6) is a secreted protein that consists of an IGFBP N-terminal domain and a thyroglobulin type-1 domain. IGFBP6 is secreted as an autocrine growth inhibitor in the human keratinocyte cell line HaCat. Recombinant IGFBP6 can inhibit the growth of HaCat cells and other keratinocyte cell lines. It also inhibits the growth of a number of IGF-II-dependent cancers including rhabdomyosarcoma, neuroblastoma, and colon cancer. | ||||
Related products | W029-3 Anti-IGFBP1 (Human) mAb M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) W147-3 Anti-TYRO3 (Human) mAb W164-3 Anti-RHBDD3 (Human) mAb |
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References |
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