MBL offers latex intermediates!
Since MBL's establishment as Japan's first antibody manufacturer, we have obtained effective antibodies in research conducted by research institutions, pharmaceutical companies, and clinical diagnostics projects. Our high-quality antibodies have been highly rated by a lot of researchers and companies alike for many years. We strive to meet our customers' needs by utilizing a variety of technologies as well as offering stellar customer service support through our extensive experience with intermediates.
What is Latex Intermediate Reagent
Latex Reagents that utilize latex agglutination and turbidimetric immunoassay (LTIA) that directly measure agglutination by antigen-antibody reaction.
We offer a wide range of bulk latex serology reagents which are ready to meet the needs of small to large companys seeking to enhance their current products volume or develop new product lines.
We offer Japan-quality products at surprisingly low prices!
Application for COVID-19 patient monitoring
According to the official COVID-19 treatment guideline in the US, China and Japan, “high CRP, high ferritin, high KL-6 levels may be associated with greater illness severity” is informed. In China, PCT is also used as an marker of greater illness severity for children.
| CDC1 | Japan MHLW2 | China NHC3 | NIH4 | |
|---|---|---|---|---|
| CRP↑ | 〇 | 〇 | 〇 | 〇 |
| Ferritin↑ | 〇 | 〇 | 〇 | 〇 |
| KL-6↑ | ― | 〇 | ― | ― |
| PCT↑(children) | ― | ― | 〇 | ― |
References:
1. Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Disease (COVID-19)
2. 新型コロナウイルス感染症（COVID-19）診療の手引き・第3版（official treatment guideline from Japan ver.3）
3. 新型冠状病毒肺炎诊疗方案（试行第八版）（Official treatment guideline from China ver.8）
4. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines
Latex Reagents Bulk List
We have products for various diseases with wide measurement ranges. New products are currently being developed at a rapid rate! We will create products that exceed customers' expectations!
The measurement range of each latex intermediate
The measurement ranges of target items
Clinical significance (one example)
- PCT
- CRP
- MMP-3
- KL-6
Advantages of measurement :The diagnosis and determination of the severity of bacterial sepsis.
Because the PCT concentration reflects the degree of inflammation due to infection, its follow-up is useful for prognostication.
Advantages of measurement :A typical inflammatory marker increased in acute inflammation or diseases that breaks down tissue.
Since it is rapidly decreased once the disease state has improved, the diagnosis of the disease state, prognostication, and determination of an appropriate therapeutic effect are possible.
Advantages of measurement :A joint destruction marker in the blood that has increased in the early phases of rheumatoid arthritis.
Blood joint destruction marker that rises early in rheumatoid arthritis.
The proliferation of the synovium in early rheumatoid arthritis can be monitored, and the prognosis of joint destruction can be predicted.
Advantages of measurement :A blood marker specific to interstitial pneumonia.
Differential diagnosis and evaluation regarding disease activity for interstitial pneumonia and other diseases are possible.
Comparison with other companies (one example)
Our products are of high quality and high sensitivity compared with products from other companies.
- PCT
- CRP
- MMP-3
- KL-6
PCT Correlation
PCT Sensitivity
CRP Correlation
CRP Sensitivity
MMP-3 Correlation
MMP-3 Sensitivity
KL-6 Correlation
KL-6 Sensitivity
Applicable Platform
| LTX intermediates | Applicable Platform (Verified) |
|---|---|
| AFP | HITACHI 7180, TOSHIBA 40FR, Beckman AU480 |
| AMH | HITACHI 7180 |
| BMG | HITACHI 7180, TOSHIBA 40FR, Beckman AU480 |
| CEA | HITACHI 7180, TOSHIBA 40FR, Mindray BS480 |
| CRP | Furuno FC800, HITACHI 7180, Dirui CS-600B |
| Cys-C | HITACHI 7180, TOSHIBA 40FR, TBA120, Beckman AU640, Mindray BS480, Dirui CS-600B |
| Ferritin | HITACHI 7180, TOSHIBA 40FR, Beckman AU480 |
| HbA1C | Furuno FC800, HITACHI 7180, Dirui CS-600B |
| H-FABP | HITACHI 7180, TOSHIBA 40FR, Beckman AU480 |
| INS | HITACHI 7180, TOSHIBA 40FR, Beckman AU480 |
| KL-6 | HITACHI 7180 |
| Mb | HITACHI 7180 |
| MMP3 | HITACHI 7180, Beckman AU680, Tokyoboueki Biolis 24I |
| NGAL | HITACHI 7180, TOSHIBA 40FR, Beckman AU640, Mindray BS480 |
| PCT | HITACHI 7180, TOSHIBA 40FR, Beckman AU480/680, Mindray BS480 |
| PG1/PG2 | HITACHI 7180, TOSHIBA 40FR, Beckman AU480 |
| PSA | HITACHI 7180, TOSHIBA 40FR, Beckman AU480, Mindray BS480 |
| RBP | HITACHI 7180, TOSHIBA 40FR, Beckman AU640 |
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