Last updated: Aug 5, 2020

MBL's Response to COVID-19

Fight against COVID-19

MBL offers clinical diagnostics and research reagents taking advantage of our strength in immunological and gene detection techniques.
Since the situation of new coronavirus (SARS-CoV-2) infection is getting worse rapidly in the world, our mission is to make contribution to protect the health of human beings and facilitate medical development. In other words, MBL group maximizes all the resources that we have to face the threat of COVID-19.

COVID-19 and PCR test
/ antibody test

COVID-19

There are seven types of coronavirus that infects human beings, in which four of these viruses diffuse for a long time that cause common cold. The rest of three types are SARS-CoV found in 2002, MERS-CoV found in 2012 and the currently spreading SARS-CoV-2 found in Dec, 2019.
Even no or slight symptoms are shown in most of the people after infection, symptoms in some of the patient can be severe and long-term. Effective treatment has not yet been found at this moment.

Reference: https://www.kantei.go.jp/jp/headline/kansensho/coronavirus.html

PCR test

PCR test

PCR test

PCR test is a genetic test that detects the presence of viruses in human body at the moment of testing. Since the virus also have genes, we can artificially amplify and detect the specific gene sequence of virus. Therefore, the specific gene of virus can be detected even in a low concentration of virus.
However, the PCR test also has its detection limit. For example, the PCR test can only test negative if there are only a few viruses in body, so in clinic, the PCR test should be used carefully with the strategies including repeatedly testing.

PCR test

PCR test

Antibody test

Antibody test

Antibody test

The purpose of virus antibody test is to check the "infection history" which tells if someone has been infected before or not. Antibody is produced by the immune cell which patrols in the human body that can respond to pathogens including viruses or cancer cells via specific reaction that attacks the pathogens or makes the pathogen unharmful.

Response of antibodies in different classes to pathogens

Response of antibodies in different classes to pathogens

There are five classes of antibodies including IgA, IgD, IgE, IgG and IgM. The most important ones in diagnostics are IgM and IgG. Normally, IgM is increased at early infection in order to respond to the pathogens instantly. IgG will be increased several days or a week later to target the specific pathogens with stronger conjugation reaction.
Even antibodies are produced in human body after the infection of SARS-CoV-2, clinical usefulness of the information to predict reviving or reinfection is still under discussion at this moment which more clinical research is required.

More information for antibody

Antibody test

Antibody test

Response of antibodies in different classes to pathogens

Response of antibodies in different classes to pathogens

COVID-19 related products

Since the situation of new coronavirus (SARS-CoV-2) infection is getting worse rapidly in the world, our mission is to make contribution to protect the health of human beings and facilitate medical development. In other words, MBL group maximizes all the resources we have to face the threaten of COVID-19.

※Caution
The following information of product is only for health workers and researchers.

PCR kit for detecting new coronavirus

MEBRIGHT SARS-CoV-2 Kit

MEBRIGHT™ SARS-CoV-2 Kit

With the genetic testing technique from our subsidiary company, G&G science, our real-time PCR kit is allowed to be commercialized in a very short time. The MEBRIGHT™ SARS-CoV-2 Kit is developed with the cooperation of NIID (National Institute of Infectious Diseases) and provides better operability using our genetic technique.

More information

MEBRIGHT SARS-CoV-2 Kit

MEBRIGHT™ SARS-CoV-2 Kit

Antibody test kit for SARS-CoV-2

SARS-CoV-2 CLIA for IgM/IgG detection 1
SARS-CoV-2 CLIA for IgM/IgG detection 2

SARS-CoV-2 CLIA for IgM/IgG detection
※iFlash 1800/3000 exclusive

MBL imports and sells the testing kit and instrument of a Chinese company, YHLO (Shenzhen YHLO Biotech Co., Ltd.), from China to Japan. YHLO is a famous IVD manufacturer that manufactures and sells IVD products in China and to Europe and other countries.
MBL has been working on diagnostic reagent business in China with a long history. Since YHLO is a very important customer for our subsidiary company, MBLB, we can import the high quality testing kit from YHLO promptly.

Please feel free to contact us

SARS-CoV-2 CLIA for IgM/IgG detection 1
SARS-CoV-2 CLIA for IgM/IgG detection 2

SARS-CoV-2 CLIA for IgM/IgG detection
※iFlash 1800/3000 exclusive

Gene extraction kit

SMITEST EX-R&D

SMITEST EX-R&D

Nucleic acid extraction reagent that can be used with MEBRIGHT™ SARS-CoV-2 kit.
The RNA samples extracted from the upper respiratory tract samples (nasopharyngeal swab samples) or lower respiratory tract samples (sputum or bronchoalveolar lavage fluid) of patient by SMITEST EX-R&D can be used with MEBRIGHT™ SARS-CoV-2 Kit.
Also, it is verified that the sample extracted from saliva can also be used.
SMITEST EX-R&D provide an efficient extraction of nucleic acid from various biological samples without harmful organic solvents such as phenol and chloroform.
There are many Citations.

More information

SMITEST EX-R&D

SMITEST EX-R&D