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HOME > Product category > RNA-RNP Network > Localization | RiboCluster Profiler

Localization


Code No. Product name Synonyms Reactivity Applications Function, localization
RN001M Anti-IGF2BP1 (IMP1) mAb IMP1, ZBP1 Hu/ Mo WB/ IP/ RIP IGF2BP1 represses translation initiation of β-actin mRNA via binding to it in nucleus and translocates to cytoplasm. When localized to destination in cytoplasm, IGF2BP1 bound to the mRNA is released from it by phosphorylation to intiate translation.
RN007P Anti-IGF2BP1 (IMP1) pAb IMP1, ZBP1 Hu/ Mo WB/ IP/ RIP/ IC/ IF IGF2BP1 represses translation initiation of β-actin mRNA via binding to it in nucleus and translocates to cytoplasm. When localized to destination in cytoplasm, IGF2BP1 bound to the mRNA is released from it by phosphorylation to intiate translation.
RN008P Anti-IGF2BP2 (IMP2) pAb IMP2 Hu/ Mo/ Rat WB/ IP/ RIP/ IC/ IF IGF2BP2 binds to the UTR of IGF2 leader 3 mRNA, which is related to development and proliferation, and regulates its translation.
RN009P Anti-IGF2BP3 (IMP3) pAb IMP3 Hu/ Mo WB/ IP/ RIP IGF2BP3 binds to the 5'-UTR of IGF2 leader 3 mRNA, which is related to development and proliferation, and regulates its translation.
RN077PW Anti-SMN1 pAb   Hu WB/ IP/ IC SMN1 regulates the localization of poly(A) RNA through interaction with HuD in mouse neuronal cell.
RN012P Anti-STAU1 (Human) pAb   Hu WB/ IP/ RIP STAU1, forms RNA granule in neuronal cells. It is reported that STAU1 regulates export and localization of mRNA via binding to dsRNAs and microtubles. It is also related to SMD (Staufen-Mediated mRNA Decay) and assembly of 40S and 60S ribosomal subunits.
RN013P Anti-STAU2 (Human) pAb   Hu WB/ IP/ RIP STAU2 is highly homologous to STAU1, but their functions may be different because they do not co-localize in neuronal cells. STAU2 shuttles between nucleus and cytoplasm, however, the function in detail is unknown.




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