Regulatory T cells (Treg) suppress overactive immune responses by inhibiting the function of activated T cells. These cells are very important for immunological tolerance to self antigens, food, etc.
Recently, it has been reported that tumors elude the immune system via this immunosuppressive function of Treg. Therefore, a method of increasing antitumor activity by suppressing or eliminating Treg is required.
MBL sells functional analysis grade antibodies which suppress tumor growth in tumor-bearing mice. We have a wide range of antibodies against Treg marker molecules such as transcriptional factor Foxp3.