Kit, protein, vector, etc detailed product information

Code No.	U-C003-01
Recombinant human CD40-ECD
Only available for the customers in Singapore, Taiwan and South Korea Storage and Stability: Recombinant CD40-ECD should be stored at -80℃ (stable for at least 1 year). The protein is stored in PBS. After thawing it should be stored in appropriate small aliquots at -20℃ or -80℃ (stable for at least 2 months). Production platform: HEK293 cells using the rPEx™ recombinant protein production platform. Datasheet URL: https://www.avsbio.com/antibodies-proteins/cd40-ecd-human
Size	100 µg
Availability (in Japan)	0 (Contact us) （In Japan at 00:05, Feb 18, 2026 in JST）
Storage temp.	-80°C
Manufacturer	AVS Bio Netherlands B.V.
Alternative names	tumor necrosis factor receptor superfamily member 5 isoform 1, TNF receptor superfamily member 5, CD40 antigen, CD40L receptor, CD40 type II isoform, nerve growth factor receptor-related B-lymphocyte activation molecule, B cell-associated molecule, B cell surface antigen CD40, tumor necrosis factor receptor superfamily member 5
Background	Product description: CD40 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Residues 21-193 of human CD40, containing the extracellular domain - ECD -, were cloned, the protein was over-expressed in HEK293 cells and was purified to homogeneity. The calculated molecular weight of recombinant human CD40-ECD is 20.5 kDa and it contains an C-terminal hexahistidine tag. Reference sequences: Swiss-prot P25942
Product category	Research area:Immunology Cell surface antigens

The availability is based on the information in Japan at 00:05, Feb 18, 2026 in JST.
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For storage temparature: RT: room temparature
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