Kit, protein, vector, etc detailed product information

Code No.	CY-8153
CircuLex Human PCSK9 Functional Assay Kit
Size	96 Assay
Availability (in Japan)	1-9 （In Japan at 00:05, Apr 26, 2024 in JST）
Components	Microplate, 10X Wash Buffer, Sample Dilution Buffer, PCSK9 Binding Activity Standard, Conjugate Dilution Buffer, 100X Biotinylated Detection Antibody, 100X HRP conjugated Streptavidin, Substrate Reagent, Stop Solution
Intended use	This kit is primarily designed for the semi-quantitative in vitro measurement of functionally active of PCSK9 in serum which is capable of binding to LDL receptor (LDLR). This kit allows to measure active PCSK9 in a solid-phase assay
Storage temp.	4°C
Manufacturer	MBL
Sample	serum, recombinant PCSK9
Measurement range	0.125 ~ 8 mAU/mL
Sensitivity	0.042 mAU/mL ~
Related products	CY-8078 CircuLex Mouse/Rat PCSK9 ELISA Kit CY-8079 CircuLex Human PCSK9 ELISA Kit CY-8150 CircuLex PCSK9-LDLR in vitro Binding Assay Kit CY-M1032 Anti-PCSK9 prodomain (Human) mAb CY-M1033 Anti-PCSK9 (Human) mAb CY-R2311 PCSK9 D374Y in culture medium CY-R2330 PCSK9 Wild Type (Human) CY-R2331 PCSK9 D374Y CY-R2333 PCSK9 R194A CY-R2340 LDLR EGF-AB domain
Product category	Research area:Metabolism Drug discovery
Data
Citations	Function Ben Djoudi Ouadda A et al. Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).Arterioscler Thromb Vasc Biol. 39, 1996-2013 (2019) (PMID:31553664)

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