Kit, protein, vector, etc detailed product information

Code No.	CY-8150
CircuLex PCSK9-LDLR in vitro Binding Assay Kit
Size	96 assays
Availability (in Japan)	0 (Contact us) （In Japan at 17:02, Jul 17, 2026 in JST）
Components	"Microplate, Recombinant His-tagged PCSK9 wild type, Biotinylated anti-His-tag monoclonal antibody, Reaction Buffer, HRP-conjugated Streptavidin, Conjugate Dilution Buffer, 10X Wash Buffer, Substrate Reagent, Stop Solution"
Intended use	This Kit is primarily designed to screening inhibitors of PCSK9-LDLR interaction in vitro.
Storage temp.	4°C
Manufacturer	MBL
Related products	CY-8078 CircuLex Mouse/Rat PCSK9 ELISA Kit CY-8079 CircuLex Human PCSK9 ELISA Kit CY-R2311 PCSK9 D374Y in culture medium CY-R2330 PCSK9 Wild Type (Human) CY-R2331 PCSK9 D374Y CY-R2333 PCSK9 R194A CY-R2340 LDLR EGF-AB domain CY-8153 CircuLex Human PCSK9 Functional Assay Kit
Product category	Research area:Metabolism Drug discovery
Citations	Lammi C et al. Lupin peptides modulate the protein-protein interaction of PCSK9 with the low density lipoprotein receptor in HepG2 cells. Sci Rep. 6, 29931 (2016)(PMID:27424515) Lammi C et al. Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity. Sci Rep. 9, 2343 (2019)(PMID:30787312) Evison BJ et al. A Small Molecule Inhibitor of PCSK9 That Antagonizes LDL Receptor Binding via Interaction With a Cryptic PCSK9 Binding Groove. Bioorg Med Chem. 28, 115344 (2020)(PMID:32051094)

The availability is based on the information in Japan at 17:02, Jul 17, 2026 in JST.
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For storage temparature: RT: room temparature
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