Kit, protein, vector, etc detailed product information

Code No. CY-1083
CycLex® c-Src Kinase Assay/Inhibitor Screening Kit
Size 96 assays
Availability (in Japan) 1-9
（In Japan at 00:05, Apr 20, 2024 in JST）
Components Microplate, 10X Wash Buffer, Kinase Buffer, 20X ATP HRP conjugated Detection Antibody Substrate Reagent, Stop Solution
Intended use This Kit is designed to measure the activities of recombinant catalytic domain of c-Src for the rapid and sensitive evaluation of inhibitors or activators.
Storage temp. 4°C
Manufacturer MBL
Related products CY-E1083 c-Src Positive Control
Product category Research area:Drug discovery Signal transduction
Citations
  1. Takuma Matsubara, Fumiyo Ikeda, Kenji Hata, Masako Nakanishi, Masato Okada, Hisataka Yasuda, Riko Nishimura, Toshiyuki Yoneda; Cbp Recruitment of Csk Into Lipid Rafts is Critical to c-Src Kinase Activity and Bone Resorption in Osteoclasts. Journal of Bone and Mineral Research, 25: 1068-1076, 2010(PMID:19874196)
  1. Al-Wadei MH et al. Gamma-amino butyric acid (GABA) prevents the induction of nicotinic receptor-regulated signaling by chronic ethanol in pancreatic cancer cells and normal duct epithelia. Cancer Prev Res. 6, 139-48 (2013)(PMID:23213073)
  1. Kang Y et al. Anti-angiogenic activity of macrolactin A and its succinyl derivative is mediated through inhibition of class I PI3K activity and its signaling. Arch Pharm Res. 38, 249-60 (2015)(PMID:25547980)
  1. Gautam J et al. Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis. Exp Mol Med. 50, 118 (2018)(PMID:30185799)
  • The availability is based on the information in Japan at 00:05, Apr 20, 2024 in JST.
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  • For storage temparature: RT: room temparature
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