Kit, protein, vector, etc detailed product information

Code No. 4800-510 プリントPrint out
Caspase-3 inhibitor Z-DEVD-FMK
Size 20 µL (100 mM)
Availability (in Japan) 10 or more
(In Japan at 17:00, Jan 17, 2022 in JST)
Storage temp. -20°C
Manufacturer MBL
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Product category Research area:Apoptosis
  1. Nakagawa Y et al. Arsenic trioxide-induced apoptosis through oxidative stress in cells of colon cancer cell lines. Life Sci. 70, 2253-69 (2002)(PMID:12005185)
  1. Kobayashi S et al. 53BP2 induces apoptosis through the mitochondrial death pathway. Genes Cells. 10, 253-60 (2005)(PMID:15743414)
  1. Nakagawa Y et al. Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorg Med Chem. 15, 5620-8 (2007)(PMID:17553685)
  1. Arimura Y et al. Effects of protein tyrosine phosphatase-PEST are reversed by Akt in T cells. Cell Signal. 26, 2721-9 (2015)(PMID:25152368)
  1. Cui X et al. Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability. Leukemia 30, 74-85 (2016)(PMID:26220042)
  1. Trillaud-Doppia E et al. A single amino acid difference between the intracellular domains of amyloid precursor protein and amyloid-like precursor protein 2 enables induction of synaptic depression and block of long-term potentiation. Neurobiol Dis. 91, 94-104 (2016)(PMID:26921470)
  1. Wang C et al. A bead-based cleavage method for large-scale identification of protease substrates. Sci Rep. 6, 22645 (2016)(PMID:26935269)
  1. Rouabhia M et al. E-Cigarette Vapor Induces an Apoptotic Response in Human Gingival Epithelial Cells Through the Caspase-3 Pathway. J Cell Physiol. 232, 1539-1547 (2017)(PMID:27808425)
  1. Tokunaga E et al. Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others. PLoS One 12, e0182152 (2017)(PMID:28763493)
  1. Chiu WT et al. Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis. Cell Death Discov. 4, 37 (2018)(PMID:29531834)
  1. Sanjo H et al. Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death. J Immunol. 203, 783-788 (2019)(PMID:31243089)
  1. Noritake K et al. Pyroptotic cell death by exposure to 1-butanol in H9c2 cardiomyoblastoma cells. Heliyon. 6, e05503 (2020) (PMID:33294662)
  1. Santoro MF et al. Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis. J Biol Chem. 273, 13119-13128 (1998)(PMID: 9582351
  2. Atkinson EA et al. Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B. J Biol Chem. 273, 21261-21266 (1998)(PMID: 9694885
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