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HOME > Product search results > Code No. CY-1173 CycLex® CaM-kinase II Assay Kit

Code No. CY-1173

CycLex® CaM-kinase II Assay Kit

Availability (in Japan)


(In Japan at 17:00,
Dec 2, 2021 in JST)


96 Assay


Components Microplate, 10X Wash Buffer, Kinase Buffer, 50X CaCl2, 50X EGTA, 20X ATP, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution
Intended use This Kit is primarily designed to measure the activities of purified Ca2+/Calmodulin dependent protein kinase II (CaM kinase II) for the rapid and sensitive evaluation of inhibitors or activators.
Storage temp. 4°C Manufacturer MBL
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  1. Yang YJ et al. Effects of scoparone on dopamine release in PC12 cells. Fitoterapia. 81, 497-502 (2010)(PMID:20080157)
  1. Bodhinathan K et al. Intracellular Redox State Alters NMDA Receptor Response during Aging through Ca2+/Calmodulin-Dependent Protein Kinase II. J Neurosci. 30, 1914-24 (2010)(PMID:20130200)
  1. Shahin R, Taha MO. Elaborate Ligand-Based Modeling and Subsequent Synthetic Exploration Unveil New Nanomolar Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitory Leads. Bioorg Med Chem. 20, 377-400 (2011)(PMID:22112539)
  1. Hamdani N et al. Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation. Circ Res. 112, 664-74 (2013)(PMID:23283722)
  1. Lu Q et al. Ca2+/calmodulin-dependent protein kinase II contributes to hypoxic ischemic cell death in neonatal hippocampal slice cultures. PLoS One. 8, e70750 (2013)(PMID:23976956)
  1. Wang N et al. Active calcium/calmodulin-dependent protein kinase II (CaMKII) regulates NMDA receptor mediated postischemic long-term potentiation (i-LTP) by promoting the interaction between CaMKII and NMDA receptors in ischemia. Neural Plast. 2014, 827161 (2014)(PMID:24734203)
  1. Chen L et al. The role of low levels of fullerene C60 nanocrystals on enhanced learning and memory of rats through persistent CaMKII activation. Biomaterials. 35, 9269-79 (2014)(PMID:25129570)
  1. Park CJ et al. Nickel affects gill and muscle development in oriental fire-bellied toad (Bombina orientalis) embryos. Aquat Toxicol. 182, 67-78 (2017)(PMID:27871005)
  1. Van Linthout S et al. Placenta-Derived Adherent Stromal Cells Improve Diabetes Mellitus-Associated Left Ventricular Diastolic Performance. Stem Cells Transl Med. 6, 2135-2145 (2017)(PMID:29024485)
  1. Miura M et al. Transient Elevation of Glucose Increases Arrhythmia Susceptibility in Non-Diabetic Rat Trabeculae With Non-Uniform Contraction. Circ J. 84, 551-558 (2020)(PMID:32092718)
  1. Herwig M et al. Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D. Front Physiol. 11, 240 (2020)(PMID:32351396)
  1. Kolijn D et al. Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator. Front Physiol. 11, 345 (2020)(PMID:32523538)
  1. Nawaratna SSK et al. Use of kinase inhibitors against schistosomes to improve and broaden praziquantel efficacy. Parasitology. 147, 1488-1498 (2020)(PMID:32741402)
  1. Miura M et al. Effect of transient elevation of glucose on contractile properties in non-diabetic rat cardiac muscle. Heart Vessels. 36, 568-576 (2021)(PMID:33226494)


  1. Ma Y et al. Atherogenic L5 LDL induces cardiomyocyte apoptosis and inhibits K ATP channels through CaMKII activation. Lipids Health Dis. 19, 189 (2020)(PMID:32825832)
Product category
Research area
Drug discovery
Signal transduction

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