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HOME > Product search results > Code No. 7625 Mouse IL-18 ELISA Kit

Code No. 7625

Mouse IL-18 ELISA Kit

Availability (in Japan)

10 or more

(In Japan at 00:05,
Sep 24, 2021 in JST)

Size

96 wells

Data

Components Microwells, Calibrator, Conjugate reagent, Conjugate diluent, Assay diluent, Wash concentrate, Substrate, Stop solution,
Intended use The Mouse IL-18 ELISA Kit is based on sandwich ELISA and is capable of measuring mouse IL-18.
Storage temp. 4°C Manufacturer MBL
Sample Serum
Sensitivity 25.0 pg/mL
Related products 7620 Human IL-18 ELISA Kit
D046-3 Anti-IL-18 (Mouse) mAb
D047-3 Anti-IL-18 (Mouse) mAb
D048-3 Anti-IL-18 (Mouse) mAb
D048-6 Anti-IL-18 (Mouse) mAb-Biotin
B002-5 Recombinant Mouse IL-18
B004-5 Recombinant Mouse IL-18 (without BSA)
D048-3M2 Anti-IL-18 (Mouse) mAb (Functional Grade)
PD039 Anti-cleaved IL-1β (Mouse) pAb
PM014 Anti-IL-18 (Human) pAb
Citations
  1. de la Roche M et al. Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol. 217, 3560-3576 (2018)(PMID:30054450)
  1. da Costa LS et al. RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux. Cell Death Dis. 10, 346 (2019)(PMID:31024004)
  1. Abdel-Nour M et al. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science. 365, pii: eaaw4144 (2019)(PMID:31273097)
  1. Quach C et al. A Truncating Mutation in the Autophagy Gene UVRAG Drives Inflammation and Tumorigenesis in Mice. Nat Commun. 10, 5681 (2019) (PMID:31831743)
  1. Sundberg JP et al. Keratinocyte-specific deletion of SHARPIN induces atopic dermatitis-like inflammation in mice. PLoS One. 15, e0235295 (2020)(PMID:32687504)
  1. Yamada K et al. Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. Transl Vis Sci Technol. 9, 1 (2020)(PMID:32855848)
  1. Chakravarti D et al. Telomere dysfunction activates YAP1 to drive tissue inflammation.Nat Commun. 11, 4766 (2020) (PMID:32958778)

ELISA

  1. Sasaki Y et al. IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell-dependent type 2 innate immunity. J Exp Med. 202, 607-16 (2005)(PMID:16129701)
  2. Banerjee S and Bond JS. Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation. J Biol Chem. 283, 31371-7 (2008)(PMID:18786924)
  3. Rodriguez-Galan MC et al. Coexpression of IL-18 strongly attenuates IL-12-induced systemic toxicity through a rapid induction of IL-10 without affecting its antitumor capacity. J Immunol. 183, 740-8 (2009)(PMID:19535628)
  4. Broz P et al. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med. 207, 1745-55 (2010)(PMID:20603313)
  5. Costa A et al. Activation of the NLRP3 inflammasome by group B streptococci. J Immunol. 188, 1953-60 (2012)(PMID:22250086)
  6. Paget C et al. Role of γδ T cells in α-galactosylceramide-mediated immunity. J Immunol. 188, 3928-39 (2012)(PMID:22412194)
  7. Grung P et al. Toll or Interleukin-1 Receptor (TIR) Domain-containing adaptor inducing interferon-  (TRIF)-mediated Caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem. 287, 34474-83 (2012)(PMID:22898816)
  8. Meldrum KK et al. Profibrotic effect of interleukin-18 in HK-2 cells is dependent on stimulation of the Toll-like receptor 4 (TLR4) promoter and increased TLR4 expression. J Biol. Chem. 287, 40391-9 (2012)(PMID:23027874)
  9. Ohkusu-Tsukada K et al. Signs of atopic dermatitis and contact dermatitis affected by distinct H2-haplotype in the NC/Nga genetic background. Sci Rep. 8, 2586 (2018)(PMID:29416104)
  10. Wang J et al. Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18. PLoS Pathog. 14, e1007105 (2018)(PMID:29791511)
  11. Funayama H et al. Effects of Zoledronate on Local and Systemic Production of IL-1β, IL-18, and TNF-α in Mice and Augmentation by Lipopolysaccharide. Biol Pharm Bull. 42 929-936 (2019)(PMID:31155589)
  12. Fang R <em>et al. ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism. Mucosal Immunol. 12, 1092-1103 (2019)(PMID:31278375)
  13. Tan S et al. H2 Protects Against Lipopolysaccharide-Induced Cardiac Dysfunction via Blocking TLR4-Mediated Cytokines Expression. Front Pharmacol. 10, 865 (2019)(PMID:31440160)
  14. Sakaguchi N et al. Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock. Front Immunol. 11, 561948 (2020) (PMID:33042141)
  15. Tourlomousis P et al. Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella. Nat Microbiol. 5, 1588-1597 (2020)(PMID:33106673)
  16. Li X et al. IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice. Sci Rep. 10, 18674 (2020)(PMID:33122671)
Product category
Research area
Immunology
Cytokine & Growth Factors
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