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HOME > Product search results > Code No. U-T006-01 Recombinant human Thrombomodulin-(his-TEV)N

Code No. U-T006-01

Recombinant human Thrombomodulin-(his-TEV)N

Availability (in Japan)

0
(Contact us)

(In Japan at 17:00,
Apr 20, 2025 in JST)

Size

100 µg

Only available for the customers in Singapore, Taiwan and South Korea

Storage and Stability:
Thrombomodulin-(his-TEV)N should be stored at -80℃ (stable for at least 1 year). The buffer is PBS without preservative. After thawing it should be stored in appropriate small aliquots at -20℃ or -80℃ (stable for at least 2 months).

Production platform:
HEK293 cells using the rPEx™ recombinant protein production platform.

Datasheet URL:
https://products.ipatherapeutics.com/product/t006/
Storage temp. -80°C Manufacturer ImmunoPrecise Antibodies (Europe) BV
Alternative names CD141, fetomodulin
Background Product description:
This glycoprotein is an endothelial-specific type I membrane receptor that binds thrombin in a 1:1 stoichiometry. This binding results in the activation of protein C, which degrades coaggulation factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. 
The mature protein of human thrombomodulin, residues 19 - 516 was over-expressed in HEK293EBNA1 cells and purified to homogeneity. The protein has 5 potential N-linked glycosylation sites and 2 potential O-linked glycosylation sites. The protein contains a N-terminal TEV protease cleavable hexahistidine tag. The calculated molecular weight without glycosylation of recombinant human thrombomodulin-(his-TEV)C, residues 19 - 516 including hexahistidine tag, is 54.9 kDa.

Reference sequences: Swiss-prot P07204
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