Availability (in Japan)
0
(Contact us)
(In Japan at 17:35,
Jan 16, 2026 in JST)
Size
100 µg
Only available for the customers in Singapore, Taiwan and South Korea
Storage and Stability:| Storage temp. | -80°C | Manufacturer | AVS Bio Netherlands B.V. | ||
|---|---|---|---|---|---|
| Alternative names | CD141, fetomodulin | ||||
| Background | Product description: This glycoprotein is an endothelial-specific type I membrane receptor that binds thrombin in a 1:1 stoichiometry. This binding results in the activation of protein C, which degrades coaggulation factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. The mature protein of human thrombomodulin, residues 19 - 516 was over-expressed in HEK293EBNA1 cells and purified to homogeneity. The protein has 5 potential N-linked glycosylation sites and 2 potential O-linked glycosylation sites. The protein contains a N-terminal TEV protease cleavable hexahistidine tag. The calculated molecular weight without glycosylation of recombinant human thrombomodulin-(his-TEV)C, residues 19 - 516 including hexahistidine tag, is 54.9 kDa. Reference sequences: Swiss-prot P07204 |
||||
| Product category |
|
||||