For purchasing or obtaining a quotation, please visit the Distributor page
to find your local distributor.
HOME > Product search results > Code No. U-P001-01 Recombinant human PDGFb

Code No. U-P001-01

Recombinant human PDGFb

Availability (in Japan)

0
(Contact us)

(In Japan at 17:00,
Feb 7, 2025 in JST)

Size

100 µg

Only available for the customers in Singapore, Taiwan and South Korea

Storage and Stability:
PDGFb should be stored at -80℃ (stable for at least 1 year). The buffer contains PBS without preservative. After thawing it should be stored in appropriate small aliquots at -20℃ or -80℃ (stable for at least 2 months).

Production platform:
HEK293 cells using the rPEx™ recombinant protein production platform.

Datasheet URL:
https://products.ipatherapeutics.com/product/p001/
Storage temp. -80°C Manufacturer ImmunoPrecise Antibodies (Europe) BV
Alternative names platelet-derived growth factor beta polypeptide, PDGF2, becaplermin, epididymis secretory sperm binding protein, proto-oncogene c-Sis
Background Product description:
Human PDGFb, platelet derived growth factor, is a dimeric protein. It can form homodimers of PDGFb or heterodimers with PDGFa. It is involved in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Mutations in PDGFb are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. 
Residues 21-211 of human PDGFb were cloned, the protein was over-expressed in HEK293EBNA1 cells and was purified to homogeneity. The calculated molecular weight of monomeric recombinant human PDGFb after propeptide removal is 15.7 kDa and 31.4 kDa for the dimeric form. The protein contains a C-terminal hexahistidine tag.

Reference sequences: Swiss-prot P01127
Product category
Research area
Cytokine & Growth Factors
Tools
Cell culture reagents
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 17:00, Feb 7, 2025 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.