Availability (in Japan)
0
(Contact us)
(In Japan at 17:00,
May 24, 2025 in JST)
Size
100 µg
Only available for the customers in Singapore, Taiwan and South Korea
Storage and Stability:Storage temp. | -80°C | Manufacturer | ImmunoPrecise Antibodies (Europe) BV | ||
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Background | Product description: Complement factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. The mature protein of complement Factor B, residues 26 - 764, was cloned and expressed in HEK293EBNA1 cells and purified to homogeneity. It contains an N-terminal hexahistidine tag. |
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