Code No. | W052-3 | Print out |
Anti-Osteopontin (SPP1) (Human) mAb | ||
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, Mar 29, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | 4A7D | |
Isotype (Immunized Animal) |
Mouse IgG2aκ | |
Applications | FCM 1-10 µg/mL |
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Immunogen (Antigen) |
Human Osteopontin (SPP1) expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening). | |
Reactivity [Gene ID] | Human[6696] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | OPN, BNSP, BSPI, ETA-1 | |
Background | Osteopontin, also known as SPP1, is a secreted phosphoglycoprotein that belongs to the SIBLING family. Osteopontin binds to hydroxyapatite and is involved in anchoring of osteoclasts to the mineral matrix of bones. It also acts as a cytokine that mediates type I immune responses through enhancing the production of interferon-gamma and interleukin-12 while reducing production of interleukin-10. Osteopontin has been identified as a biomarker for ovarian cancer, prostate cancer, and non-small cell lung cancer. | |
Related products | M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) D050-3 Anti-CD29 (Integrin β1) (Human) mAb W164-3 Anti-RHBDD3 (Human) mAb |
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Product category | Research area:Stem cell research Cancer Cytokine & Growth Factors Tools:Flow cytometry reagents |
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Data | ||
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