Antibody detailed product information

Code No.	W046-3
Anti-CD201 (EPCR) (Human) mAb
Size	100 µL (1 mg/mL)
Availability (in Japan)	10 or more （In Japan at 00:05, Apr 16, 2024 in JST）
Clonality	Monoclonal
Clone	4B9D
Isotype (Immunized Animal)	Mouse IgG2aκ
Applications	FCM　1-10 µg/mL
Immunogen (Antigen)	Human CD201 (EPCR) expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity [Gene ID]	Human[10544]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Alternative names	CCCA, CCD41, PROCR
Background	Endothelial protein C receptor (EPCR), also known as PROCR or CD201, is an N-glycosylated type I membrane protein and functions as a receptor of activated protein C, which is a serine protease involved in the blood coagulation pathway. EPCR is highly expressed in the endothelial cells of arteries and veins in the heart and lung. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction. It has also been suggested that EPCR is involved in the development of human breast cancer and lung cancer.
Related products	M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) W164-3 Anti-RHBDD3 (Human) mAb
Product category	Research area:Immunology Cancer Cell surface antigens Tools:Flow cytometry reagents
Data
References	Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat. Biotechnol. 17, 487-490 (1999)（PMID: 10331810）

The availability is based on the information in Japan at 00:05, Apr 16, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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