Code No. | RN123PW | Print out |
Anti-YTHDF2 pAb | ||
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:00, Mar 29, 2024 in JST) |
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Clonality | Polyclonal | |
Clone | Polyclonal | |
Isotype (Immunized Animal) |
Rabbit Ig (aff.) | |
Applications | WB 1:1,000 IP 5 µL/500 µL of cell extract from 5 x 106 cells/sample IC* reported. (PMID: 30065315) |
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Reactivity [Gene ID] | Human[51441], Mouse[213541], Rat(w)[313953], Hamster[100763174] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | CAHL, HGRG8, NY-REN-2 | |
Background | N(6)-methyladenosine (m6A) is one of the most abundant modified nucleosides found in some viral RNA and eukaryotic RNA including mRNA, tRNA, rRNA and lncRNA. It has been reported that m6A modification is involved in the regulation of mRNA export, stability and translation. YTH N(6)-methyladenosine RNA binding protein 2 (YTHDF2), functioning as m6A reader protein, is involved in methylation-dependent RNA degradation. YTHDF2 selectively binds to m6A-containing RNA through its C-terminal domain and its N-terminal domain is required for localization of the protein-m6A-containing RNA complex to P-body. | |
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Product category | Research area:RNA-RNP Network Epigenetics Cancer | |
Data | ||
Citations | Western Blotting
Immunocytochemistry
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