Code No. | D367-3 | |
Anti-HLA class I (HLA-A,B,C) (Human) mAb | ||
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 0 (Contact us) (In Japan at 17:33, Apr 26, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | EMR8-5 | |
Isotype (Immunized Animal) |
Mouse IgG1 κ | |
Applications | WB 1 µg/mL FCM 1 µg/mL IH |
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Immunogen (Antigen) |
Recombinant HLA-A*2402 extracellular domain | |
Reactivity [Gene ID] | ||
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | major histocompatibility complex, class I, HLA-A, HLAA/HLA-B, AS, HLAB, SPDA1/HLC-C, D6S204, PSORS1, HLA-JY3 | |
Background | Human major histocompatibility complex (MHC) class I antigen-epitope peptide complex associated with β2-microglobulin are expressed by all human nucleated cells. It plays an important role in cell-mediated immune responses. Abnormalities in MHC class I antigen surface expression are frequently found in malignancies and infectious diseases. They are often associated with reduced recognition by MHC class I antigen-restricted, tumor or virus-associated antigen-specific cytotoxic T lymphocytes and disease progression. The EMR8-5 monoclonal antibody reacts with a non-polymorphic epitope of human MHC class I antigens, HLA-A, -B, and -C. | |
Related products | K0126-3 Anti-HLA-E (Human) mAb K0215-3 Anti-HLA-E (Human) mAb K0208-3 Anti-HLA-A24 (Human) mAb K0208-4 Anti-HLA-A24 (Human) mAb-FITC K0208-5 Anti-HLA-A24 (Human) mAb-PE K0208-A48 Anti-HLA-A24 (Human) mAb-Alexa Fluor™ 488 K0208-A64 Anti-HLA-A24 (Human) mAb-Alexa Fluor™ 647 K0209-3 Anti-HLA-A24 (Human) mAb K0209-4 Anti-HLA-A24 (Human) mAb-FITC K0209-5 Anti-HLA-A24 (Human) mAb-PE D370-3H Anti-HLA class I (HLA-A,B,C) (Human) mAb |
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Product category | Research area:Immunology Cancer Cell surface antigens | |
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