Antibody detailed product information

Code No. D349-3
Anti-CLOCK mAb
This antibody reacts with mouse and human Clock.
Size 100 µL (1 mg/mL)
Availability (in Japan) 10 or more
（In Japan at 00:05, Jul 23, 2026 in JST）
Clonality Monoclonal
Clone CLSP4
Isotype
(Immunized Animal) 		Mouse IgG1 κ
Applications WB　1 µg/mL  
IP　2 µg/sample  
IH　
ChIP*　reported.  （PMID: 24591654）
Immunogen
(Antigen)		 MBP-Ser/Pro-rich region (Ser377-Glu556) of mouse CLOCK
Reactivity [Gene ID]

Human[9575], Mouse[12753]
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names KAT13D, bHLHe8, mKIAA0334, 5330400M04Rik, circadian locomotor output cycles kaput
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Product category Research area:Circadian rhythm Signal transduction
Data





Citations

Western Blotting

  1. Tsurudome Y et al. Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function. Sci Rep. 8, 9072 (2018)(PMID:29899468)
  2. Umemura Y et al. Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development. Proc Natl Acad Sci U S A. 114, E7479-E7488 (2017)(PMID:28827343)

ChIP

  1. Yoshitane H et al. CLOCK-controlled polyphonic regulation of circadian rhythms through canonical and noncanonical E-boxes. Mol Cell Biol 34, 1776–87 (2014)(PMID:24591654)
  2. Doi Met al. Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity. Nat Commun. 10, 2563 (2019)(PMID:31189882)

Immunoprecipitation

  1. Yoshitane H et al. Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription. Mol Cell Biol 29, 3675-3686 (2009)(PMID:19414601)

Immunocytochemistry

  1. Umemura Y et al. Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development. Proc Natl Acad Sci U S A. 114, E7479-E7488 (2017) (PMID:28827343)

Immunohistochemistry

  1. Umemura Y et al. Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development. Proc Natl Acad Sci U S A. 114, E7479-E7488 (2017) (PMID:28827343)
  2. Ohashi M et al. Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors. Genes Cells. 23, 60-69 (2018)(PMID:29271044)
References
  1. Yoshitane H et al. CLOCK-controlled polyphonic regulation of circadian rhythms through canonical and noncanonical E-boxes. Mol Cell Biol 34, 1776–87 (2014) (PMID: 24591654) [ChIP]
  • The availability is based on the information in Japan at 00:05, Jul 23, 2026 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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