Antibody detailed product information

Code No.	D299-3
Anti-IDH1-R132H (Human) mAb
Not available for the customers in the US and EU This clone reacts with mutated IDH1-R132H and does not cross-react with wild type IDH1 and other IDH1 mutants.
Size	100 µg/100 µL
Availability (in Japan)	10 or more （In Japan at 00:05, Jul 23, 2026 in JST）
Clonality	Monoclonal
Clone	HMab-1
Isotype (Immunized Animal)	Mouse IgG1 κ
Applications	WB　5-10 µg/mL IP　10 µg/100 µg Lysate IC　5 µg/mL IH　5 µg/mL
Reactivity [Gene ID]	Human[3417](PMID: 22396072), Hamster(-), Dog*[478889](PMID: 29285579)
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Alternative names	isocitrate dehydrogenase 1 (NADP+), soluble
Related products	D309-3 Anti-IDH1 mAb D300-3 Anti-IDH1-R132S (Human) mAb D328-3 Anti-IDH2-R172K (Human) mAb D330-3 Anti-IDH2 mAb D331-3 Anti-IDH1-R132G (Human) mAb D336-3 Anti-IDH1 mAb D337-3 Anti-IDH2-R172M (Human) mAb D338-3 Anti-IDH2-R172W (Human) mAb D332-3 Anti-Mutated IDH1/2 (Human) mAb
Product category	Research area:Cancer Neuroscience
Data
Citations	Western Blotting Kawakami S et al. R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes. Vet Res Commun. 42, 49-56 (2018)(PMID:29285579) Li S et al. Mutation of IDH1 aggravates the fatty acid‑induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain. Mol Med Rep. 19, 2509-2518 (2019)(PMID:30720071) Immunocytochemistry Kawakami S et al. R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes. Vet Res Commun. 42, 49-56 (2018)(PMID:29285579) Immunohistochemistry Takano S et al. Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. J Neurooncol. 108, 361-73 (2012)(PMID:22396072) Ishikawa E et al. Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. J Neurosurg. 121, 543-53 (2014)(PMID:24995786) Fukami S et al. Pathologic Findings and Clinical Course of Midline Paraventricular Gliomas Diagnosed Using a Neuroendoscope. World Neurosurg. 114, e366-e377 (2018)(PMID:29530692) Liu R et al. Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance. Nat Commun. 10, 991 (2019) (PMID:30824700)

The availability is based on the information in Japan at 00:05, Jul 23, 2026 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.