Code No. | D281-6 | Print out |
Anti-CD61 (GPIIIa) (Human) mAb-Biotin | ||
Size | 50 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, Mar 29, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | T74 | |
Isotype (Immunized Animal) |
Mouse IgG1 κ | |
Applications | FCM 1 µg/mL (final concentration) ELISA Can be used. |
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Immunogen (Antigen) |
Human thrombocyte | |
Reactivity [Gene ID] | Human[3690] |
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Storage buffer | 1 mg/mL in PBS/1% BSA/0.1% ProClin 150 | |
Storage temp. | 4°C | |
Conjugate | Biotin | |
Manufacturer | MBL | |
Alternative names | ITGB3, integrin subunit beta 3, GP3A | |
Background | Glycoprotein IIIa, a β3 (CD61) subunit of integrin αIIbβ3 (CD41/CD61), acts as a fibrinogen receptor on the platelet surface. A mouse monoclonal antibody, T74, recognizes human β3 (CD61) subunit and inhibits platelet aggregation induced by several agonists such as collagen, ADP, and thrombin. T74 inhibits clot-retraction mediated by platelets or αvβ3-expressing cells when induced by thrombin. Western-blot analysis is not possible. T74 fails to bind to platelets from patients with Glanzmann’s thrombasthenia. | |
Related products | D281-3 Anti-CD61 (GPIIIa) (Human) mAb |
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Product category | Research area:Immunology Cell surface antigens Exosomes | |
Data | ||
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