Antibody detailed product information

Code No. D266-3
Anti-Mincle (Mouse) mAb
Size 100 µL (1 mg/mL)
Availability (in Japan) 10 or more
（In Japan at 17:33, Apr 26, 2024 in JST）
Clonality Monoclonal
Clone 1B6
Isotype
(Immunized Animal) 		Rat IgG1 κ
Applications WB　1 µg/mL  
IP　2 µg/2.0 x 106 cells/sample  
FCM　2 µg/mL  
Function　1-10 µg/mL (for blocking)  （PMID: 18776906 / 23602766）
Immunogen
(Antigen)		 RBL-2H3 cells expressing full-length mouse mincle
Reactivity [Gene ID]

Mouse[56619]
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names C-type lectin domain family 4, member e, Clec4e C86253 Clecsf9
Related products D292-3 Anti-Mincle (Mouse) mAb
M191-3 Anti-FcεR1γ (FcRγ) (Mouse) mAb
D266-3M2 Anti-Mincle (Mouse) mAb (Functional Grade)
D292-3M2 Anti-Mincle (Mouse) mAb (Functional Grade)
D360-3 Anti-Mincle (Human) mAb (Functional Grade)
D266-6 Anti-Mincle (Mouse) mAb-Biotin
Product category Research area:Immunology
Data



Citations

Western Blotting

  1. Yamasaki S et al. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol. 9, 1179-88 (2008)(PMID:18776906)
  2. Yamasaki S et al. C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. PNAS 106, 1897-902 (2009)(PMID:19171887)

Flow Cytometry

  1. Yamasaki S et al. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol. 9, 1179-88 (2008)(PMID:18776906)
  2. Miyake Y et al. C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.　Immunity. 38, 1050-62 (2013)(PMID:23602766)
  3. Yamasaki S et al. C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. PNAS 106, 1897-902 (2009)(PMID:19171887)

Function

  1. Yamasaki S et al. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol. 9, 1179-88 (2008)(PMID:18776906)
  2. Miyake Y et al. C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.　Immunity. 38, 1050-62 (2013)(PMID:23602766)
  3. Ishikawa E et al. Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J Exp Med. 206, 2879-88 (2009)(PMID:20008526)
  4. Yamasaki S et al. C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. PNAS 106, 1897-902 (2009)(PMID:19171887)
  • The availability is based on the information in Japan at 17:33, Apr 26, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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