Antibody detailed product information

Code No. D134-3
Anti-HES1 mAb
Size 100 µL (1 mg/mL)
Availability (in Japan) 1-9
（In Japan at 00:05, Apr 20, 2024 in JST）
Clonality Monoclonal
Clone NM1
Isotype
(Immunized Animal) 		Rat IgG2a
Applications WB　0.1-1 µg/mL  
IP　2 µg/300 µL of cell extract  
IC　10-20 µg/mL  
IH*　reported.  （PMID: 17360543 / 17183323 / 21116324）
Immunogen
(Antigen)		 Rat full length HES1 (1-281 a.a.)
Reactivity [Gene ID]

Human*[3280](PMID: 21116324/ 19151708/ 21238798), Mouse*[15205](PMID: 17183323/ 17360543/ 19481797), Rat[29577]
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names hairy and enhancer of split 1 (Drosophila), Hry, bHLHb39
Related products D130-3 Anti-Runx2 (Cbfa1) mAb
PD022 Anti-Pax6 pAb
Product category Research area:Cancer Neuroscience
Data



Citations

Western Blotting

  1. Rustighi A et al. The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer. Nat Cell Biol. 11, 133-42 (2009)(PMID:19151708)

Immunoprecipitation

  1. Rustighi A et al. The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer. Nat Cell Biol. 11, 133-42 (2009)(PMID:19151708)

Immunohistochemistry

  1. Shitamukai A et al. Oblique radial glial divisions in the developing mouse neocortex induce self-renewing progenitors outside the germinal zone that resemble primate outer subventricular zone progenitors. J Neurosci. 31, 3683-95 (2011)(PMID:21389223)
  2. Vasyutina E et al. RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells. PNAS 104, 4443-8 (2007)(PMID:17360543)
  3. Cao L et al. Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling. Biomaterials. 30, 4085-93 (2009)(PMID:19481797)
  4. Meliou E et al. Immunohistochemical expression of Notch signaling in the lining epithelium of periapical cysts. J Endod. 37, 176-80 (2011)(PMID:21238798)
  5. Meliou E et al. Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study). Open Dent J. 4, 153-8 (2010)(PMID:21116324)
  6. Ridgway J et al. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature. 444, 1083-7 (2006)(PMID:17183323)
  • The availability is based on the information in Japan at 00:05, Apr 20, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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