Antibody detailed product information

Code No.	CY-P1025
Anti-Phospho-MBS (MYPT1) (Thr853) pAb
Size	50 µg
Availability (in Japan)	1-9 （In Japan at 17:33, Apr 26, 2024 in JST）
Clonality	Polyclonal
Clone	Polyclonal
Isotype (Immunized Animal)	Rabbit IgG
Applications	WB　0.4-1 µg/mL ELISA　0.5-1 μg/mL
Immunogen (Antigen)	a synthetic phosphopeptide corresponding to residues surrounding Thr853 of human MBS/MYPT1 (KLH-conjugated )
Reactivity [Gene ID]	Human[4659], Mouse[17931], Rat[116670], Chicken
Storage buffer	0.5 mg/mL in 10 mM HEPES KOH/150 mM NaCl/50% glycerol, pH 7.5
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Alternative names	PPP1R12A; protein phosphatase 1, regulatory subunit 12A, MBS; M130; MYPT1/Mypt1; AA792106; AV099298; D10Ertd625e; 1200015F06Rik; 5730577I22Rik/M110; MBSP; Mypt1
Product category	Research area:Drug discovery Signal transduction
Data
Citations	Isgro J et al. Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus. Arthritis Rheum. 65, 1592-602 (2013)(PMID:23508371) Gabrielli L et al. Increased rho-kinase activity in hypertensive patients with left ventricular hypertrophy. Am J Hypertens. 27, 838-45 (2014)(PMID:24363278) Western Blotting Ocaranza MP et al. Rho-kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with reduced ejection fraction. J Cell Mol Med. 24, 1413-1427 (2019)(PMID:31778027) Ocaranza MP et al. Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2. Cardiovasc Diabetol. 19, 56 (2020)(PMID:32375786)

The availability is based on the information in Japan at 17:33, Apr 26, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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