Antibody detailed product information

Code No. BMP052
Anti-SLC6A14 (ATB0+) (Human) pAb
Size 50 µL
Availability (in Japan) 10 or more
（In Japan at 17:00, Apr 20, 2024 in JST）
Clonality Polyclonal
Clone Polyclonal
Isotype
(Immunized Animal) 		Rabbit Ig (aff.)
Applications WB　1:1,000  
FCM　1:1,000  
IC　1:1,000  
IH　1:5,000 (Heat treatment is necessary for paraffin embedded sections.)  
Immunogen
(Antigen)		 Human SLC6A14-derived synthetic peptide
Reactivity [Gene ID]

Human[11254]
Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names solute carrier family 6 member 14, BMIQ11
Background SLC6A14, also known as ATB0+, is a member of the Na+ - and Cl- - dependent neurotransmitter transporter family, and is highly expressed in the lung, fetal lung, trachea, and salivary gland. SLC6A14 transports both neutral and cationic amino acids, and has about 60% amino acid similarity with the glycine transporters GLYT1 and GLYT2. The blockade of ATB0+ in cancer cell lines is associated with cell cycle arrest, indicating the potential of ATB0+ as a drug target in cancer chemotherapy.
Related products PM035 Normal Rabbit IgG
Data




Citations

Western Blotting

  1. Wongthai P et al. Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2. Cancer Sci. 106, 279-86 (2015)(PMID:25580517)
  • The availability is based on the information in Japan at 17:00, Apr 20, 2024 in JST.
  • The special price is shown in red color.
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  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
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