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HOME > Product search results > Code No. W072-3
Anti-CD358 (DR6) (Human) mAb
Code No. W072-3
Anti-CD358 (DR6) (Human) mAb
Availability (in Japan)
1-9
（In Japan at 00:05,
Dec 5, 2024 in JST）
Size
100 µL (1 mg/mL)
Data Sheet| Data |
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| Clonality | Monoclonal | Clone | 3E2E4 | ||
| Isotype (Immunized Animal) | Mouse IgG2aκ | ||||
| Applications |
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| Immunogen (Antigen) | Human CD358 (DR6) expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening). | ||||
| Reactivity [Gene ID] | Human[27242] |
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| Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
| Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
| Alternative names | TNFRSF21, BM-018 | ||||
| Background | Death receptor 6 (DR6), also known as CD358 or TNFRSF21, is a member of the tumor necrosis factor receptor superfamily. DR6 contains a death domain and four TNFR-Cys repeats. It is highly expressed in the heart, brain, placenta, pancreas, lymph nodes, thymus, and prostate. DR6 activates nuclear factor kappa-B and mitogen-activated protein kinase 8 and induces cell apoptosis. Overexpression of DR6 has been observed in several cancers including ovarian cancer and sarcoma. | ||||
| Related products | M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) D297-3 Anti-p75NTR (Mouse) mAb M009-3 Anti-Amyloid Precursor Protein mAb W164-3 Anti-RHBDD3 (Human) mAb |
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- The availability is based on the information in Japan at 00:05, Dec 5, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.