Anti-G3BP1 pAb

Availability (in Japan)

10 or more

（In Japan at 17:00,
Dec 4, 2024 in JST）

Size

100 µL

Citations

Data Sheet

SDS

Data	Western Blotting Immunoprecipitation
Clonality	Polyclonal	Clone	Polyclonal
Isotype (Immunized Animal)	Rabbit Ig (aff.)
Applications	WB 1:1,000 IP 5 µL/500 µL cell extract from 5 x 10⁶ cells IC* reported. （PMID: 26990993 / 29373831）
Immunogen (Antigen)	KLH conjugated synthetic peptide, corresponding to internal region of human G3BP1
Reactivity [Gene ID]	Human[10146], Mouse(-), Rat(-), Hamster(-)
Storage buffer	PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	GTPase activating protein (SH3 domain) binding protein 1, G3BP, HDH-VIII
Background	G3BP1, a DNA/RNA helicase, plays a role in regulation of mRNA export, mRNA decay and stabilization. G3BP1 is known as a component of stress granule required for the formation of stress guranule.
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Citations	Immunocytochemistry Sundararaman B et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 61, 903-13 (2016)(PMID:26990993) Markmiller S et al. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell 172, 590-604.e13 (2018)(PMID:29373831) Koyuncu S et al. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Nat Commun. 9, 2886 (2018)(PMID:30038412)
Product category	Research area RNA-RNP Network Brands RiboCluster Profiler™

The availability is based on the information in Japan at 17:00, Dec 4, 2024 in JST.
The special price is shown in red color.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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