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Product search results > Code No. K0227-4
Anti-CD8 (Mouse) mAb-FITC
Code No. K0227-4
Anti-CD8 (Mouse) mAb-FITC
Availability (in Japan)
10 or more
（In Japan at 00:05,
Apr 18, 2024 in JST）
Size
1 mL (100 tests)
Data Sheet| Data |
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| Clonality | Monoclonal | Clone | KT15 | ||
| Isotype (Immunized Animal) | Rat IgG2aλ | ||||
| Applications |
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| Immunogen (Antigen) | T cell clone C6, H-2Kk restricted H-Y antigen specific CTL | ||||
| Reactivity [Gene ID] | Mouse[12525] |
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| Storage buffer | PBS/1% BSA/0.1% ProClin 150 | ||||
| Storage temp. | 4°C | Conjugate | FITC | Manufacturer | MBL |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. CD8 α chains bind to class-I MHC molecules α3 domains. CD8 identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.This monoclonal antibody KT15 reacts with a non-polymorphic epitope on the mouse CD8 α chain (mouse Ly2.1 and Ly2.2 cells). | ||||
| Related products | M081-4 Rat IgG2a (isotype control)-FITC D341-4 Anti-CD4 (Mouse) mAb-FITC |
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- The availability is based on the information in Japan at 00:05, Apr 18, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.