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Product search results > Code No. D344-3MS
Anti-Phospho-p62 (SQSTM1) (Ser403) mAb for My select sampler set
Code No. D344-3MS
Anti-Phospho-p62 (SQSTM1) (Ser403) mAb for My select sampler set
Availability (in Japan)
0
(Contact us)
（In Japan at 00:05,
Apr 17, 2024 in JST）
Size
20 µL (1 mg/mL)
Data Sheet| Data |
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| Clonality | Monoclonal | Clone | 4C8 | ||
| Isotype (Immunized Animal) | Rat IgG2aκ | ||||
| Applications |
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| Immunogen (Antigen) | synthetic peptide CKKKESLSQMLpSMGFSDEGKKK (corresponding to amino acid residues 396-410 of human p62 (SQSTM1)) | ||||
| Reactivity [Gene ID] | |||||
| Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
| Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
| Alternative names | sequestosome-1, A170, OSIL, PDB3, ZIP3 | ||||
| Background | p62/SQSTM1 is a major adaptor protein for selective autophagy. S403 is in a highly conserved ubiquitin association (UBA) domain of p62 and is directly phosphorylated by CK2 or TBK1. The S403 phosphorylation of p62 results in the enhanced binding affinity between p62 and polyubiquitin chain and induces its autophagic degradation. S403 phosphorylated p62 is concentrated in autophagosomes that is accumulated by Bafilomycin A1 treatment and in ubiquitin positive protein aggregates in autophagy deficient cells.
Clone 4C8 recognizes S403-phosphoryalted p62, but is different from clone 4F6. |
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| Related products | D343-3 Anti-Phospho-p62 (SQSTM1) (Ser403) mAb PM074 Anti-Phospho-p62 (SQSTM1) (Ser351) pAb PM045 Anti-p62 (SQSTM1) pAb M162-3 Anti-p62 (SQSTM1) (Human) mAb PM066 Anti-p62 C-terminal pAb M162-A48 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 488 M162-A59 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 594 M162-A64 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 647 |
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- The availability is based on the information in Japan at 00:05, Apr 17, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.