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HOME > Product search results > Code No. D233-3 Anti-Mesothelin (Mouse) mAb

Code No.　D233-3

Anti-Mesothelin (Mouse) mAb

Availability (in Japan)

1-9

（In Japan at 00:05,
Apr 19, 2024 in JST）

Size

100 µL (1 mg/mL)

Data

  • Flow Cytometry
Clonality Monoclonal Clone B35
Isotype (Immunized Animal) Rat IgG2a
Applications
FCM
10 µg/mL  
Function*
reported.  （PMID: 28287406）
Immunogen (Antigen) Mouse hemangioblast-like cell line LO cells
Reactivity [Gene ID]

Mouse[56047]
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names Msln, MPF
Background Mesothelin (MSLN) is a GPI-linked cell surface glycoprotein expressed in the mesothelial lining of the body cavities and in mullerian duct epithelium related cancer cells (ovarian, pancreatic cancer, mesothelioma). Both human and mouse mesothelin bind to ovarian cancer antigen CA125/MUC16 with high affinity, mediating cell attachment in vitro, suggesting that mesothelin may facilitate ovarian cancer metastasis.
Related products D233-3 Anti-Mesothelin (Mouse) mAb
M081-3 Rat IgG2a (isotype control)
Citations

Function

  1. Koyama Y et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 127,1254-1270 (2017)(PMID:28287406)
Product category
Research area
Cancer
Cell surface antigens
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.