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HOME > Product search results > Code No. D204-5 Anti-CD52 (CAMPATH-1) (Mouse) mAb-PE

Code No. D204-5

Anti-CD52 (CAMPATH-1) (Mouse) mAb-PE

Availability (in Japan)

10 or more

(In Japan at 00:05,
Apr 19, 2024 in JST)

Size

1 mL (50 tests)

Clonality Monoclonal Clone BTG-2G
Isotype (Immunized Animal) Rat IgG2aκ
Applications
FCM
20 µL  
Immunogen (Antigen) mouse IL-2Rα-transgenic mice splenocyte
Reactivity [Gene ID]

Mouse[23833]

Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C Conjugate PE Manufacturer MBL
Alternative names B7, MB7, CLS1, B7-Ag
Background CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa; however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.
Related products D204-3 Anti-CD52 (CAMPATH-1) (Mouse) mAb
D204-4 Anti-CD52 (CAMPATH-1) (Mouse) mAb-FITC
Product category
Research area
Immunology
Cancer
Cell surface antigens
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.