Anti-CD52 (CAMPATH-1) (Mouse) mAb-FITC

Availability (in Japan)

10 or more

（In Japan at 17:00,
Apr 19, 2024 in JST）

Size

100 µL (500 µg/mL)

Clonality	Monoclonal	Clone	BTG-2G
Isotype (Immunized Animal)	Rat IgG2aκ
Applications	FCM 20 µg/mL (final concentration)
Immunogen (Antigen)	mouse IL-2Ralpha-transgenic mice splenocytes
Reactivity [Gene ID]	Mouse[23833]
Storage buffer	500 µg/mL in PBS/1% BSA/0.1% ProClin150
Storage temp.	4°C	Conjugate	FITC	Manufacturer	MBL
Background	CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa; however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.
Related products	D204-5 Anti-CD52 (CAMPATH-1) (Mouse) mAb-PE D204-3 Anti-CD52 (CAMPATH-1) (Mouse) mAb
Product category	Research area Immunology Cancer Cell surface antigens

The availability is based on the information in Japan at 17:00, Apr 19, 2024 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.