Anti-SLC6A6 (TAUT) (Human) pAb

Availability (in Japan)

10 or more

（In Japan at 17:00,
Apr 24, 2024 in JST）

Size

50 µL

Citations

Data Sheet

SDS

Data	Flow Cytometry Immunocytochemistry Immunohistochemistry
Clonality	Polyclonal	Clone	polyclonal
Isotype (Immunized Animal)	Rabbit Ig (aff.)
Applications	FCM 1:200 IC 1:200 IH 1:5,000 (Heat treatment is necessary for paraffin embedded sections.) WB* reported. （PMID: 22619065）
Immunogen (Antigen)	Human SLC6A6-derived synthetic peptide
Reactivity [Gene ID]	Human[6533], Other* (Japanese eel (PMID: 22619065))
Storage buffer	PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	solute carrier family 6 (neurotransmitter transporter, taurine), member 6
Background	SLC6A6, also known as TAUT, belongs to the neurotransmitter transporter family and transports taurine in a Na+- and Cl–-dependent manner. Taurine is involved in many important physiological processes, including antioxidation, osmolarity regulation, and proper maintenance of the functions of the liver and skeletal muscles. Since fetuses and neonates cannot independently synthesize taurine, they depend on taurine supplied through the placenta and breast milk of their mothers for their development. According to a recent report, rat SLC6A6 also appears to transport another neurotransmitter, namely, GABA, across the inner blood-retinal barrier.
Related products	BMP029 Anti-SLC6A2 (NET) (Human) pAb BMP045 Anti-SLC6A4 (SERT) (Human) pAb BMP046 Anti-SLC6A6 (TAUT) (Human) pAb BMP053 Anti-SLC6A19 (B⁰AT1) (Human) pAb BMP091 Anti-SLC6A9 (GlyT1) (Human) pAb BMP052 Anti-SLC6A14 (ATB⁰⁺) (Human) pAb
Citations	Western Blotting Higuchi M et al. Taurine plays an important role in the protection of spermatogonia from oxidative stress. Amino Acids. 43, 2359-2369 (2012)(PMID:22619065) Immunohistochemistry Higuchi M et al. Taurine plays an important role in the protection of spermatogonia from oxidative stress. Amino Acids. 43, 2359-2369 (2012)(PMID:22619065)

The availability is based on the information in Japan at 17:00, Apr 24, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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