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HOME > Product search results > Code No. PM064 Anti-Lamin B1 pAb

Code No.　PM064

Anti-Lamin B1 pAb

Availability (in Japan)

10 or more

（In Japan at 00:05,
Apr 16, 2024 in JST）

Size

100 µL

This Lamin B1 polyclonal antibody is an effective nuclear envelope marker for Immunocytochemistry, Western blotting and Immunoprecipitation.
Data

  • Western Blotting

  • Immunoprecipitation

  • Immunocytochemistry
Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:1,000  
IP
5 µL/300 µL of cell extract from 3 x 106 cells  
IC
1:200  
Immunogen (Antigen) KLH conjugated synthetic peptide corresponding to C-terminus of human Lamin B1
Reactivity [Gene ID]

Human[4001], Mouse[16906], Rat[116685], Hamster[103161362]
Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names ADLD, LMN, LMN2, LMNB
Background Lamin B1 is one of the component proteins of the nuclear lamina that is a dense fibrous network and lies on the inner surface of the inner nuclear membrane. The nuclear lamina plays an essential role in chromatin organization, cell cycle regulation, DNA replication, cell differentiation and apoptosis.
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Citations

Western Blotting

  1. Jia X et al. The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model. Life Sci. 90, 934-43 (2012)(PMID:22569299)
  2. Jia X et al. Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats. Dig Dis Sci. 58, 2212-22 (2013)(PMID:23824403)
  3. Yamamoto N et al. Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells. Virus Res. 178, 404-10 (2013)(PMID:24070983)
  4. Mukai R, Ohshima T. HTLV-1 HBZ positively regulates the mTOR signaling pathway via inhibition of GADD34 activity in the cytoplasm.Oncogene 33, 2317-28 (2014)23708656(PMID:23708656)
  5. Qu L et al. hCINAP negatively regulates NF-κB signaling by recruiting the phosphatase PP1 to deactivate IKK complex. J Mol Cell Biol. 7, 529-42 (2015)(PMID:26089539)
  6. Bai D et al. The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth. Nat Commun. 7, 12310 (2016)(PMID:27477389)
  7. Hirano K, Namihira M. FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1. FEBS Open Bio. 7, 1932-1942 (2017)(PMID:29226080)
  8. Mizunoe Y et al. Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways. Redox Biol. 15, 115-124 (2017)(PMID:29241092)
  9. Kaneko H et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 50, 527-535 (2018)(PMID:29523960)
  10. Endo H et al. Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells. Sci Rep. 8, 10122 (2018)(PMID:29973599)
  11. Fujii N et al. Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue. Exp Gerontol. 118, 55-64 (2019) (PMID:30620889)
  12. Xu R et al. hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy. Nat Commun. 10, 3812 (2019)(PMID:31444354)
  13. Mizunoe Y et al. Cathepsin B Overexpression Induces Degradation of Perilipin 1 to Cause Lipid Metabolism Dysfunction in Adipocytes. Sci Rep. 10, 634 (2020)(PMID:31959889)
  14. Endo H et al. Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment. Redox Biol. 36, 101643 (2020)(PMID:32863227)
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  • The availability is based on the information in Japan at 00:05, Apr 16, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.