Anti-IDH2-R172K (Human) mAb

Availability (in Japan)

10 or more

（In Japan at 17:00,
Apr 19, 2024 in JST）

Size

100 µL (1 mg/mL)

Data	Western Blotting
Clonality	Monoclonal	Clone	KMab-1
Isotype (Immunized Animal)	Rat IgG2bκ
Applications	WB 1 µg/mL IC* reported. （PMID: 29162772）
Reactivity [Gene ID]	Human[3418](PMID: 23376717), Dog*[479043](PMID: 29162772)
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	mNADP-IDH, isocitrate dehydrogenase 2 (NADP+), mitochondrial
Related products	D309-3 Anti-IDH1 mAb D299-3 Anti-IDH1-R132H (Human) mAb D300-3 Anti-IDH1-R132S (Human) mAb D330-3 Anti-IDH2 mAb D331-3 Anti-IDH1-R132G (Human) mAb D336-3 Anti-IDH1 mAb D337-3 Anti-IDH2-R172M (Human) mAb D338-3 Anti-IDH2-R172W (Human) mAb D332-3 Anti-Mutated IDH1/2 (Human) mAb
Citations	Western Blotting Kaneko MK et al. Establishment of novel monoclonal antibodies KMab-1 and MMab-1 specific for IDH2 mutations Biochem Biophys Res Commun. 432, 40-5 (2013)(PMID:23376717) Kawakami S et al. Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation. J Vet Med Sci. 80, 85-91 (2018) (PMID:29162772) Gao M et al. Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants. Cancer Sci. 110, 3306-3314 (2019)(PMID:31361380) Immunocytochemistry Kawakami S et al. Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation. J Vet Med Sci. 80, 85-91 (2018) (PMID:29162772)
Product category	Research area Cancer Neuroscience

The availability is based on the information in Japan at 17:00, Apr 19, 2024 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.