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HOME > Product search results > Code No. D217-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)

Code No.　D217-3

Anti-Desmoglein 3 (Mouse) mAb (No Azide)

Availability (in Japan)

10 or more

（In Japan at 00:05,
Apr 18, 2024 in JST）

Size

100 µL (1 mg/mL)

Data

  • Immunocytochemistry

  • Immunohistochemistry
Clonality Monoclonal Clone AK9
Isotype (Immunized Animal) Mouse IgG1
Applications
IP
reported.  （PMID: 12574390）
IC
0.01 µg/mL  
IH
0.01 µg/mL  
Immunogen (Antigen) hybridoma was established by fusion of splenocytes from PV model mouse and P3 mouse myeloma cells
Reactivity [Gene ID]

Human(-), Mouse[13512]
Storage buffer 1 mg/mL in PBS, pH 7.2
Storage temp. 4°C Conjugate Unlabeled Manufacturer MBL
Alternative names Dsg3
Background Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein.
Related products D218-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)
D219-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)
M075-3 Mouse IgG1 (isotype control)
Citations

Immunoprecipitation

  1. Tsunoda K, et al., Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170:2170-8. 2003(PMID:12574390)

Immunohistochemistry

  1. Yamaguchi T, et al., Identification of the Staphylococcus aureus etd pathogenicity island which encodes a novel exfoliative toxin, ETD, and EDIN-B. Infect Immun. 70:5835-45. 2002(PMID:12228315)
Product category
Research area
Immunology
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  • The availability is based on the information in Japan at 00:05, Apr 18, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
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