Code No. | RN017M | |
Anti-7-methylguanosine (m7G) mAb | ||
This antibody (clone 4141-13) reacts with both 5′-terminal and internal 7-methylguanosine (m7G) in RNA. | ||
Size | 200 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, May 13, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | 4141-13 | |
Isotype (Immunized Animal) |
Mouse IgG2aκ | |
Applications | IP 10 µg/sample IC Can be used. ELISA Can be used. DB 1 µg/mL Other(Northwestern blotting) reported. (PMID: 29983320) |
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Immunogen (Antigen) |
Carrier protein-conjugated 7-methylguanosine (m7G)-Cap analogue | |
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Background | The 7-methylguanosine (m7G) is a modified nucleoside commonly found in eukaryotes. The m7G modification present on the 5′-end of mRNA and on some ncRNA synthesized by RNA polymerase II is called m7G cap. It plays a role in transcription, splicing, polyadenylation, nuclear export, stabilization, and translation. In addition, other m7G modifications are also found in the tRNA or rRNA. The m7G46 modification occurs in bacterial and eukaryotic tRNAs. The m7G1575 modification in the 18S rRNA is evolutionarily conserved in eukaryotes. | |
Related products | RN016M Anti-7-methylguanosine (m7G)-Cap mAb RN1005 RIP-Assay Kit for microRNA D347-3 Anti-Pseudouridine mAb D345-3 Anti-1-methyladenosine (m1A) mAb D346-3 Anti-5-methylcytidine (m5C) mAb PM077 Anti-5-hydroxymethylcytosine (5hmC) pAb MI-11-3 Anti-Bromodeoxyuridine mAb MI-11-5 Anti-Bromodeoxyuridine mAb-PE M218-3 Anti-5-hydroxymethylcytosine (5hmC) mAb M227-3 Anti-Digoxigenin (DIG) mAb M228-3 Anti-FITC mAb RN019M Anti-2,2,7-trimethylguanosine (m3G/TMG) mAb RN006M Anti-EIF4E mAb RN001P Anti-EIF4E pAb RN126PW Anti-AHCY (SAHH) pAb RN124PW Anti-RNMT (Human) pAb PM098 Anti-Inosine pAb |
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Product category | Research area:RNA-RNP Network Epigenetics Brands:RiboCluster Profiler™ |
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Data | ||
Citations | Immunoprecipitation
RNP Immunoprecipitation
Other(Northwestern blotting)
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References |
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